Emerging Infectious Diseases (Aug 2018)

Distinguishing Zika and Dengue Viruses through Simple Clinical Assessment, Singapore

  • Gabriel Yan,
  • Long Pang,
  • Alex R. Cook,
  • Hanley J. Ho,
  • Mar Soe Win,
  • Ai Leng Khoo,
  • Joshua G.X. Wong,
  • Chun Kiat Lee,
  • Benedict Yan,
  • Roland Jureen,
  • Siew Seen Ho,
  • David C. Lye,
  • Paul A. Tambyah,
  • Yee Sin Leo,
  • Dale Fisher,
  • Jolene Oon,
  • Natasha Bagdasarian,
  • Angela Chow,
  • Nares Smitasin,
  • Louis Yi Ann Chai

DOI
https://doi.org/10.3201/eid2408.171883
Journal volume & issue
Vol. 24, no. 8
pp. 1565 – 1568

Abstract

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Dengue virus and Zika virus coexist in tropical regions in Asia where healthcare resources are limited; differentiating the 2 viruses is challenging. We showed in a case–control discovery cohort, and replicated in a validation cohort, that the diagnostic indices of conjunctivitis, platelet count, and monocyte count reliably distinguished between these viruses.

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