Indirect targeting of MYC sensitizes pancreatic cancer cells to mechanistic target of rapamycin (mTOR) inhibition

• Christian Schneeweis,
• Zonera Hassan,
• Katja Ascherl,
• Matthias Wirth,
• Stella Koutsouli,
• Felix Orben,
• Lukas Krauß,
• Carolin Schneider,
• Rupert Öllinger,
• Oliver H. Krämer,
• Roland Rad,
• Maximilian Reichert,
• Maria S. Robles,
• Dieter Saur,
• Günter Schneider

Affiliations

Christian Schneeweis

Medical Clinic and Polyclinic II Klinikum rechts der Isar Technical University Munich Munich 81675 Germany

Zonera Hassan

Medical Clinic and Polyclinic II Klinikum rechts der Isar Technical University Munich Munich 81675 Germany

Katja Ascherl

Medical Clinic and Polyclinic II Klinikum rechts der Isar Technical University Munich Munich 81675 Germany

Matthias Wirth

Department of Hematology Oncology and Tumor Immunology Charité ‐ Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin, Humboldt‐Universität zu Berlin and Berlin Institute of Health Berlin 12203 Germany

Stella Koutsouli

Institute of Medical Psychology and Biomedical Center (BMC) Faculty of Medicine LMU Munich Munich 80336 Germany

Felix Orben

Medical Clinic and Polyclinic II Klinikum rechts der Isar Technical University Munich Munich 81675 Germany

Lukas Krauß

Medical Clinic and Polyclinic II Klinikum rechts der Isar Technical University Munich Munich 81675 Germany

Carolin Schneider

Medical Clinic and Polyclinic II Klinikum rechts der Isar Technical University Munich Munich 81675 Germany

Rupert Öllinger

Institute of Molecular Oncology and Functional Genomics TUM School of Medicine Technical University Munich Munich 81675 Germany

Oliver H. Krämer

Department of Toxicology University of Mainz Medical Center Mainz 55131 Germany

Roland Rad

Institute of Molecular Oncology and Functional Genomics TUM School of Medicine Technical University Munich Munich 81675 Germany

Maximilian Reichert

Medical Clinic and Polyclinic II Klinikum rechts der Isar Technical University Munich Munich 81675 Germany

Maria S. Robles

Institute of Medical Psychology and Biomedical Center (BMC) Faculty of Medicine LMU Munich Munich 80336 Germany

Dieter Saur

German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK) Heidelberg 69120 Germany

Günter Schneider

Medical Clinic and Polyclinic II Klinikum rechts der Isar Technical University Munich Munich 81675 Germany