Malignant eyelid tumors: epidemiology and clinical observation of patients in Moscow

Abstract

Purpose: to assess the prevalence of primary malignant eyelid tumors and their prognostic features based on the materials of the ocular oncology department, Moscow Ophthalmological Center. Materials and methods. We performed a retrospective analysis of 10-year array (2010–2019) of documents of the Moscow Cancer Register, reports of the ocular oncology department of the Moscow ophthalmological center, S.P. Botkin State Clinical Hospital, and case histories of outpatients with malignant eyelid tumors, residing in Moscow. Results. Malignant ocular tumors were diagnosed in 3650 people. Of these, 75.29 % were eyelid tumors (2748 people). The most common malignant tumor was basal cell carcinoma (89.19 %), which was morphologically diagnosed and over the ten years showed an incidence increase of almost a third. The occurrence rate grows with age, with the peak observed between 70 and 79 years of life. Most often, the lower eyelid (64%) and the inner corner (22.14 %) are affected. Less common are tumors located in the upper eyelid (12.21 %) and at the lateral canthus — 2.3 %. Over 80 % of the relapses occurred at the T2–T3 stages, while only 18.2 % were eyelid skin cancers treated at the T1 stage. Tumors located in the inner corner of the palpebral fissure recurred up to 3 times more often than differently localized eyelid tumors. Conclusion. Malignant eyelid tumors are the most common of malignant ocular neoplasms, claiming ¾ of them. Basal cell carcinoma is the most common type. The peak incidence falls upon the 7th and the 8th decades of life. An increase in the incidence of malignant tumors of the eyelids is observed. The special ophthalmic-oncological service facilitates the diagnostics, treatment and dispensary observation of patients after treatment, which contributes to the early detection of relapses.

Keywords

• malignant eyelid tumors
• basal cell carcinoma
• eyelid tumors