The experience of free light chains of immunoglobulin elimination in patients with monoclonal gammopathies

Abstract

The objective of study is to estimate the efficiency of extracorporeal free light chains of immunoglobulin elimination in patients with monoclonal gammopathies (n = 12) during hemodialysis using selective filters.Materials and methods. A blood and dialysate free light chains concentrations change was criterion of efficiency.Results and conclusion. The selective free light chains filtration give the possibility of an adequate anti-tumor therapy, could prevent the development of irreversible renal failure and hypoalbuminemia.

Keywords

• free light chains of immunoglobulin
• monoclonal gammopathies
• multiple myeloma
• lymphoma
• extracorporeal detoxification