Study of Cytotoxic and Antibacterial Activity of Ag‐ and Mg‐Dual‐Doped ZnO Nanoparticles

Abstract

Abstract A non‐laborious process for the fabrication of silver and magnesium dual doped zinc oxide nanoparticles (Ag/Mg−ZnO NP) is described. The wurtzite ZnO nano‐structures and the dual doped NP were analyzed by PXRD. SEM data showed the hexagonal morphology of our product, while the gathered anti‐bacterial outcomes towards Streptococcus mutans bacteria through micro‐dilution technic affirmed the enhanced performance of doped NP compared to the native ones. Furthermore, we gauged the toxic impacts of synthesized pure and Ag/Mg−ZnO NP against a breast cancer (MDA‐MB‐231) cell line through an MTT trial, which highlighted the superiority of the doped when compared to the native nanoparticles. In light of these comparisons, the applicability of Ag/Mg−ZnO NP in dental and medical science is proposed.

Keywords

• Ag/Mg−ZnO
• human breast cancer
• Streptococcus mutans
• Scanning Electron Microscopy
• well-diffusion