Nonthermal Plasma-Mediated Cancer Cell Death; Targeted Cancer Treatment

Abstract

Non-thermal air plasma can kill cancer cells. However, there is no selectivity between normal and cancer cells. Therefore, cancer specific antibody conjugated gold nanoparticle (GNP) was pretreated before plasma irradiation. Stimulation of antibody conjugated GNP by plasma treatment resulted in a significant decrease in viability of cancer cells. This technology shows the feasibility of using plasma therapy for killing cancer cells selectively.

Keywords

• cancer cell death
• non-thermal plasma
• gold nanoparticle
• antibody