Highly Efficient Mono-Functionalization of Knob-in-Hole Antibodies with Strain-Promoted Click Chemistry

• Jorick J. Bruins,
• Criss van de Wouw,
• Koen Wagner,
• Lina Bartels,
• Bauke Albada,
• Floris L. van Delft

Affiliations

Jorick J. Bruins

Laboratory of Organic Chemistry, Wageningen University & Research, Wageningen, The Netherlands

Criss van de Wouw

Laboratory of Organic Chemistry, Wageningen University & Research, Wageningen, The Netherlands

Koen Wagner

AIMM Therapeutics, Amsterdam, The Netherlands

Lina Bartels

AIMM Therapeutics, Amsterdam, The Netherlands

Bauke Albada

Laboratory of Organic Chemistry, Wageningen University & Research, Wageningen, The Netherlands

Floris L. van Delft

Laboratory of Organic Chemistry, Wageningen University & Research, Wageningen, The Netherlands