Two cases of male breast cancer at a university hospital in southeast Brazil

Abstract

Fabiana Resende Rodrigues,1 André Vallejo da Silva,2 Calina Maria Loures de Oliveira Teixeira,2 Samantha Cunha Gomes Antunes,2 Mayra Carrijo Rochael11Pathology Service, Pathology Department, 2Breast Service, Maternal and Infant Department, Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Niterói, Rio de Janeiro, Brazil Abstract: We report two rare cases of breast cancer in men treated with modified radical mastectomy. The patients were aged 67 and 45 years at the time of diagnosis. Tumor sizes were 2 cm and 8 cm in the older and younger patient, respectively. The histopathologic diagnosis was infiltrating ductal carcinoma in the first patient and infiltrating papillary carcinoma in the second patient. Immunohistochemical tests demonstrated estrogen and progesterone receptor positivity and HER2/c-erbB-2 negativity in both cases. The rarity of these cases is noted, in view of their uncommon occurrence at an early age in men and their immunophenotypic positivity, similar to breast cancer in women.Keywords: breast cancer, men, histopathology, immunohistochemistry, radical mastectomy