Correlation of different inflammatory and biochemical parameters in Covid-19 patients- A retrospective study

Abstract

Background: The Covid-19 pandemic is not just a challenge for health care systems; it is also a huge economic burden. One way to minimize this burden is by allocating the resources in proper direction for the management of the disease. Aims and Objectives: To correlate among the following inflammatory and biochemical markers, CRP, LDH, Troponin-I, Ferritin and D-dimer. Materials and Methods: The study population includes all the laboratory data of Covid 19 patients of KIMS hospital from May 2020 to October 2020. The parameters included in the study are C-Reactive protein (CRP), Ferritin, Lactate Dehydrogenase (LDH), Troponin I, D- dimer. CRP and LDH were estimated by micro-slide method, Ferritin and Troponin I were estimated by Chemiluminescence immunoassay and D-dimer was estimated by turbidimetric immunoassay. Results: The parameters CRP, Ferritin, LDH and D-dimer were positively correlated with each other, but none of them showed statistically significant correlation. Troponin-I did not show any correlation with the other parameters. Conclusion: We conclude that no isolated parameter individually is beneficial in covid-19 management and choice of parameter need to be based on merit of case or associated complications.

Keywords

• correlation
• covid-19
• laboratory parameters