Characteristics of induced sputum neutrophils and macrophages in patients with chronic obstructive pulmonary disease on a basic therapy

Abstract

Aim of the research — to define the tiotropium bromide influence on bronchial neutrophiles and macrophages morphofunctional properties at stable of chronic obstructive pulmonary disease (COPD). The tiotropium using for 3 months has allowed to improve essentially qualitative characteristics of key effectors cells. The revealed changes were observed in all groups of patients irrespective of a previous mode of COPD treatment.

Keywords

• хроническая обструктивная болезнь легких
• нейтрофилы
• макрофаги
• миелопероксидаза
• катионный протеин