A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries

Takahiro Kuchimaru; Naoya Kataoka; Kenji Nakagawa; Tatsuhiro Isozaki; Hitomi Miyabara; Misa Minegishi; Tetsuya Kadonosono; Shinae Kizaka-Kondoh

doi:10.1038/s41467-018-05366-3

Nature Communications (Jul 2018)

A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries

Takahiro Kuchimaru,
Naoya Kataoka,
Kenji Nakagawa,
Tatsuhiro Isozaki,
Hitomi Miyabara,
Misa Minegishi,
Tetsuya Kadonosono,
Shinae Kizaka-Kondoh

Affiliations

Takahiro Kuchimaru: School of Life Science and Technology, Tokyo Institute of Technology
Naoya Kataoka: School of Life Science and Technology, Tokyo Institute of Technology
Kenji Nakagawa: School of Life Science and Technology, Tokyo Institute of Technology
Tatsuhiro Isozaki: School of Life Science and Technology, Tokyo Institute of Technology
Hitomi Miyabara: School of Life Science and Technology, Tokyo Institute of Technology
Misa Minegishi: School of Life Science and Technology, Tokyo Institute of Technology
Tetsuya Kadonosono: School of Life Science and Technology, Tokyo Institute of Technology
Shinae Kizaka-Kondoh: School of Life Science and Technology, Tokyo Institute of Technology

DOI: https://doi.org/10.1038/s41467-018-05366-3
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 7

Abstract

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Reliably modelling bone metastasis in mice is essential for research. Here, the authors present a new murine model for cancer metastasis based on intra-caudal artery injection that reliably recapitulates bone metastasis.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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