Indirect protection from vaccinating children against influenza in households

Tim K. Tsang; Vicky J. Fang; Dennis K. M. Ip; Ranawaka A. P. M. Perera; Hau Chi So; Gabriel M. Leung; J. S. Malik Peiris; Benjamin J. Cowling; Simon Cauchemez

doi:10.1038/s41467-018-08036-6

Nature Communications (Jan 2019)

Indirect protection from vaccinating children against influenza in households

Tim K. Tsang,
Vicky J. Fang,
Dennis K. M. Ip,
Ranawaka A. P. M. Perera,
Hau Chi So,
Gabriel M. Leung,
J. S. Malik Peiris,
Benjamin J. Cowling,
Simon Cauchemez

Affiliations

Tim K. Tsang: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong
Vicky J. Fang: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong
Dennis K. M. Ip: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong
Ranawaka A. P. M. Perera: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong
Hau Chi So: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong
Gabriel M. Leung: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong
J. S. Malik Peiris: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong
Benjamin J. Cowling: WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong
Simon Cauchemez: Mathematical Modelling of Infectious Diseases Unit, Institut Pasteur

DOI: https://doi.org/10.1038/s41467-018-08036-6
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 7

Abstract

Read online

Relevance of indirect protection of household members of vaccinees is unclear. Here, Tsang et al. quantify the direct and indirect protection of vaccination in a randomized controlled trial and show that benefits of individual vaccination remain important even when other household members are vaccinated.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal