Synthesis of Polyfluorinated KRN7000 Analogues and Biological Implications

M. Isabel Matheu; David Collado; Miquel Mulero; Yolanda Díaz; Sergio Castillón; Omar Boutureira

doi:10.3390/proceedings2019022089

Proceedings (Aug 2019)

Synthesis of Polyfluorinated KRN7000 Analogues and Biological Implications

M. Isabel Matheu,
David Collado,
Miquel Mulero,
Yolanda Díaz,
Sergio Castillón,
Omar Boutureira

Affiliations

M. Isabel Matheu: Analytical Chemistry and Organic Chemistry Department, Faculty of Chemistry, Sescelades Campus, University Rovira i Virgili, 43002 Tarragona, Spain
David Collado: Analytical Chemistry and Organic Chemistry Department, Faculty of Chemistry, Sescelades Campus, University Rovira i Virgili, 43002 Tarragona, Spain
Miquel Mulero: Analytical Chemistry and Organic Chemistry Department, Faculty of Chemistry, Sescelades Campus, University Rovira i Virgili, 43002 Tarragona, Spain
Yolanda Díaz: Analytical Chemistry and Organic Chemistry Department, Faculty of Chemistry, Sescelades Campus, University Rovira i Virgili, 43002 Tarragona, Spain
Sergio Castillón: Analytical Chemistry and Organic Chemistry Department, Faculty of Chemistry, Sescelades Campus, University Rovira i Virgili, 43002 Tarragona, Spain
Omar Boutureira: Analytical Chemistry and Organic Chemistry Department, Faculty of Chemistry, Sescelades Campus, University Rovira i Virgili, 43002 Tarragona, Spain

DOI: https://doi.org/10.3390/proceedings2019022089
Journal volume & issue: Vol. 22, no. 1
p. 89

Abstract

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KRN7000 is a synthetic glycosphingolipid developed as an anticancer drug candidate, whichupon association with the CD1d protein activates NKT cells. [...]

Published in Proceedings

ISSN: 2504-3900 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: General Works
Website: http://www.mdpi.com/journal/proceedings

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