EFFECTS OF CARBOXIN ON GLUTATHIONE REDUCTASE ENZYME ACTIVITY IN RAINBOW TROUT (Oncorhynchus mykiss)

Abstract

Carboxin is one of the most widely used fungicides in agriculture, but information about toxicity on fish is limited.This study assessed the effects of exposure to to carboxin on the antioxidant defence system of rainbow trout (Oncorhynchus mykiss). The fish were exposed to carboxin (3,85 ppm) for seven days. And antioxidant parameter (glutathione reductase, (GR)) was measured in hepar. The results indicated that carboxin exposure significantly affected the activity of GR in fish hepar (plt; 0.01). Thus, it was assumed that carboxin caused oxidative stress in rainbow trout and GR enzyme played a role in protection against carboxin toxicity.

Keywords

• Karboksin, gökkuşağı alabalığı, toksisite, antioksidan enzim, GR