ITGAL as a prognostic biomarker correlated with immune infiltrates in melanoma

TengFei Deng; Chaoyong Wang; Cong Gao; Qiang Zhang; Jun Guo

doi:10.3389/fonc.2023.1181537

Frontiers in Oncology (Jun 2023)

ITGAL as a prognostic biomarker correlated with immune infiltrates in melanoma

TengFei Deng,
Chaoyong Wang,
Cong Gao,
Qiang Zhang,
Jun Guo

Affiliations

TengFei Deng: Plastic Surgery Department, Yangzhou University Affiliated Hospital, Yangzhou, China
Chaoyong Wang: Medical College of Yangzhou University, Yangzhou, China
Cong Gao: Plastic Surgery Department, Yangzhou University Affiliated Hospital, Yangzhou, China
Qiang Zhang: Plastic Surgery Department, Yangzhou University Affiliated Hospital, Yangzhou, China
Jun Guo: Plastic Surgery Department, Yangzhou University Affiliated Hospital, Yangzhou, China

DOI: https://doi.org/10.3389/fonc.2023.1181537
Journal volume & issue: Vol. 13

Abstract

Read online

This study investigates the relationship between ITGAL expression and immune infiltration, clinical prognosis, and specific types of T cells in melanoma tissue. The findings reveal the key role of ITGAL in melanoma and its potential mechanism of regulating tumor immune infiltrating cells, highlighting its potential as a diagnostic biomarker and therapeutic target for advanced melanoma.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

About the journal

Abstract

Keywords