Hematology, Transfusion and Cell Therapy (Jul 2019)

Proposal of treatment algorithm for immune thromocytopenia in adult patients of a hematology service at a referral center in Northeastern Brazil

  • Rosângela de Albuquerque Ribeiro,
  • Gentil Claudino de Galiza Neto,
  • Amanda da Silva Furtado,
  • Lucas Loiola Ponte Albuquerque Ribeiro,
  • Marcela Sobreira Kubrusly,
  • Elsie Sobreira Kubrusly

Journal volume & issue
Vol. 41, no. 3
pp. 253 – 261

Abstract

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Introduction: The management of adult (≥18 years) immune thrombocytopenia patients relies on platelet count, the risk of bleeding and presence of bleeding. Objective: Confirming the diagnosis of immune thrombocytopenia and the start of therapy, our hematology service, a referral center, favors the establishment of this algorithm to treat those patients. Results: Presentation, recently diagnosed or recurrence – group 1: life-threatening bleeding: high-dose intravenous immunoglobulins with methylprednisolone or dexamethasone. Hospitalization and platelet transfusion are considered. Group 2: Platelets 20 × 109/L and stop bleeding. Keywords: Thrombocytopenia, Immune, Adults, Drug, Therapy