Bordetella pertussis Clones Identified by Multilocus Variable-Number Tandem-Repeat Analysis

Abstract

Multilocus variable-number tandem-repeat analysis (MLVA) of 316 Bordetella pertussis isolates collected over 40 years from Australia and 3 other continents identified 66 MLVA types (MTs), including 6 predominant MTs. Typing of genes encoding acellular vaccine antigens showed changes that may be vaccine driven in 2 MTs prevalent in Australia.

Keywords

• multilocus variable-number tandem-repeat analysis
• acellular vaccine antigenic variation
• Bordetella pertussis
• global epidemiology
• bacteria
• dispatch