Specific Effects of Some Metabolic Syndrome Components on Kidney Stone Formation: A Multicentric Multidisciplinary Study

Abstract

Objective:In this study, we examined the effects of dyslipidemia, obesity, non-alcoholic fatty liver disease and atherosclerosis on kidney stone formation.Materials and Methods:Patients were divided into two groups; group 1; 300 patients having kidney stones or not group 2; 528 patients. Among these patients’ triglyceride, cholesterol, high-density lipoprotein and low-density lipoprotein values; non-alcoholic fatty liver disease, atherosclerosis, waist circumference and subcutaneous adipose tissue thickness were recorded.Results:It was determined that the presence of non-alcoholic fatty liver disease, atherosclerosis, high-density lipoprotein, low-density lipoprotein and cholesterol levels and subcutaneous adipose tissue thickness did not have any effect on developing kidney stones. However, triglyceride level and waist circumference had a statistically significant effect on kidney stone formation.Conclusion:Considering that the presence of high triglyceride and low waist circumference levels can cause kidney stones in the patient; then the formation of kidney stones can be avoided by eliminating these factors through preventable or treatable modifications.

Keywords

• atherosclerosis
• dyslipidemia
• kidney stones
• non-alcoholic fatty liver
• obesity