On demand delivery and analysis of single molecules on a programmable nanopore-optofluidic device

M. Rahman; M. A. Stott; M. Harrington; Y. Li; M. J. N. Sampad; L. Lancaster; T. D. Yuzvinsky; H. F. Noller; A. R. Hawkins; H. Schmidt

doi:10.1038/s41467-019-11723-7

Nature Communications (Aug 2019)

On demand delivery and analysis of single molecules on a programmable nanopore-optofluidic device

M. Rahman,
M. A. Stott,
M. Harrington,
Y. Li,
M. J. N. Sampad,
L. Lancaster,
T. D. Yuzvinsky,
H. F. Noller,
A. R. Hawkins,
H. Schmidt

Affiliations

M. Rahman: School of Engineering, University of California Santa Cruz
M. A. Stott: ECEn Department, Brigham Young University
M. Harrington: School of Engineering, University of California Santa Cruz
Y. Li: School of Engineering, University of California Santa Cruz
M. J. N. Sampad: School of Engineering, University of California Santa Cruz
L. Lancaster: Department of Molecular, Cell and Developmental Biology and Center for Molecular Biology of RNA, University of California at Santa Cruz
T. D. Yuzvinsky: School of Engineering, University of California Santa Cruz
H. F. Noller: Department of Molecular, Cell and Developmental Biology and Center for Molecular Biology of RNA, University of California at Santa Cruz
A. R. Hawkins: ECEn Department, Brigham Young University
H. Schmidt: School of Engineering, University of California Santa Cruz

DOI: https://doi.org/10.1038/s41467-019-11723-7
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 7

Abstract

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Nanopore based detection has numerous high impact applications outside of next-generation sequencing. Here the authors use an optofluidic chip to detect individual individual 70S ribosomes in a sample mixed with DNA.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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