Diagnosis of disturbed lipid and carbohydrate metabolism in hypertensive women in outpatient setting

Abstract

Aim. To study lipid and carbohydrate metabolism in young and middle-aged women with essential hypertension (EH). Material and methods. Anthropometric parameters, arterial pressure (AP), glucose tolerance (GT), fasting glucose, immunoreactive insulin (IRI), glycosylated hemoglobin (HbA), total cholesterol (TC), triglycerides (TG), HDLP cholesterol, atherogenic index were estimated in 93 women aged 20 to 50 years with EH stage II. Results. TC was elevated in 75%, HDLP cholesterol - in 52%, TG - in 40% patients. Subnormal HDLP was only in 8% examinees. 6, 4, 21% of 53 examinees had elevated fasting glucose, GT, HbA„ respectively. Hyperinsulinemia was detected in 80%, insulin resistance in 92%. Conclusion. Disturbances of lipid metabolism were identified in more than half of the examined EH women. The HbAt test is more sensitive than GT and fasting glucose tests in detection of abnormal carbohydrate metabolism.

Keywords

• essential hypertension
• disturbances of carbohydrate and lipid metabolism
• diagnosis
• glycosylated hemoglobin