Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4

Samantha Khoury; Alireza Ahadi; Xiaoying Zhang; Nham Tran

doi:10.1016/j.gdata.2016.04.007

Genomics Data (Jun 2016)

Expression of microRNAs in HPV negative tonsil cancers and their regulation of PDCD4

Samantha Khoury,
Alireza Ahadi,
Xiaoying Zhang,
Nham Tran

Affiliations

Samantha Khoury: Centre for Health Technologies, Faculty of Engineering and Information Technology, University of Technology, Sydney, Australia
Alireza Ahadi: Centre for Health Technologies, Faculty of Engineering and Information Technology, University of Technology, Sydney, Australia
Xiaoying Zhang: The Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Australia
Nham Tran: Centre for Health Technologies, Faculty of Engineering and Information Technology, University of Technology, Sydney, Australia

DOI: https://doi.org/10.1016/j.gdata.2016.04.007
Journal volume & issue: Vol. 8, no. C
pp. 93 – 96

Abstract

Read online

Global rates of tonsil cancer have been increasing since the turn of the millennia, however we still have a limited understanding of the genes and pathways which control this disease. This array dataset which is linked to our publication (Zhang et al., 2015) describes the profiling of human miRNAs in tonsil and normal adjacent tissues. With this dataset, we identified a list of microRNA (miRNA) which were highly over represented in tonsil cancers and showed that several miRNAs were able to regulate the tumour suppressor PDCD4 in a temporal manner. The dataset has been deposited into Gene Expression Omnibus (GSE75630).

Published in Genomics Data

ISSN: 2213-5960 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Biology (General): Genetics
Website: http://www.journals.elsevier.com/genomics-data/

About the journal