eJHaem (Aug 2021)

Applicability of Western protocols in resource‐limited setting: Real‐world data of long‐term outcome of intensive treatment of adult acute myeloid leukaemia in Sri Lanka

  • Saman Hewamana,
  • Lakmali Kandabadage,
  • Thurairajah Skandarajah,
  • Natasha Pieris,
  • Eranga Perera,
  • Mahesh Harischandra,
  • Ananda Wijewickrama,
  • Chandana Wickramarathna,
  • Gnani Somasundaram,
  • Vadivelu Srinivasan,
  • Surjit Somiah,
  • Priyankara Jayawardena,
  • Mehendra Perera,
  • Dehan Gunasekera,
  • Chathuri Jayasinghe,
  • Godvin Constantine,
  • Sanjeewa Munasinghe,
  • Chandu De Silva,
  • Bandula Wijesiriwardena,
  • Jayantha Balawardena

DOI
https://doi.org/10.1002/jha2.191
Journal volume & issue
Vol. 2, no. 3
pp. 555 – 561

Abstract

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Abstract There are no published data on long‐term survival and applicability of treatment protocols from developed countries in acute myeloid leukaemia (AML) in Sri Lanka. Eighty‐seven AML patients were reviewed; there were 56 newly diagnosed patients between 18 and 65 years. Thirty‐one out of 33 who started treatment achieved complete remission after first cycle of treatment. The induction mortality was one of 33. Twelve out of 20 patients who completed treatment are alive at the time of analysis. The estimated 5‐year overall survival rate is 0.629. Strict infection control and treatment and superior clinical experience may have contributed towards better outcome.

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