Antibiotics (Oct 2024)

Antibiotic Prophylaxis and Treatment for Cardiac Device Infections

  • Claudio Pandozi,
  • Andrea Matteucci,
  • Carlo Pignalberi,
  • Luca Sgarra,
  • Michela Bonanni,
  • Marco Valerio Mariani,
  • Vincenzo Mirco La Fazia,
  • Lorenzo Nesti,
  • Stefania Angela Di Fusco,
  • Federico Nardi,
  • Furio Colivicchi

DOI
https://doi.org/10.3390/antibiotics13100991
Journal volume & issue
Vol. 13, no. 10
p. 991

Abstract

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Cardiac device infections (CDIs) are a serious complication in patients with implanted devices, resulting in increased morbidity, prolonged hospital stay, and increased healthcare costs. The effective management of these infections involves a combination of appropriate antibiotic therapy and preventive strategies aimed at reducing the risk of infection. The role of antibiotic prophylaxis in infection prevention is crucial, including the emerging use of antibiotic-supported tools and other local antibiotic delivery systems, which may reduce the risk of infection at the device implant site. In this contemporary review, we provide an overview of the prophylactic treatment and different antibiotic regimens for the treatment of CDIs, emphasizing early diagnosis, appropriate choice of antibiotics, and individualized treatment.

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