Pharmaceutics (Aug 2021)

Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair

  • Eliana B. Souto,
  • Cristiana M. P. Yoshida,
  • Gislaine R. Leonardi,
  • Amanda Cano,
  • Elena Sanchez-Lopez,
  • Aleksandra Zielinska,
  • César Viseras,
  • Patricia Severino,
  • Classius F. da Silva,
  • Raquel de M. Barbosa

DOI
https://doi.org/10.3390/pharmaceutics13081199
Journal volume & issue
Vol. 13, no. 8
p. 1199

Abstract

Read online

The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually used in polymeric-based film formulations due to their plasticizing action, with a view to improving the mechanical properties of these films. On the other hand, many lipids have healing, antimicrobial, anti-inflammatory, anti-aging properties, among others, that make them even more interesting for application in the medical-pharmaceutical field. This manuscript discusses the production methods of these films both on a laboratory and at industrial scales, the properties of the developed biopolymers, and their advantages for the development of dermatologic and cosmetic products.

Keywords