Evaluasi Tingkat Migrasi Neutrofil (OMR) dalam Mulut pada Mahasiswa FKG UI dengan Stres Akademik

Abstract

A study has been done on the relationship between anxiety and migration rate of PMN in the mouth. Subjects were dental students of University of Indonesia from the first and the third semester, consisting of 12 males and 97 females, 19-25 years old, and not suffering from any physical diseases or psychotic disorders. This study had a within-subject design with each student as his or her own control. Observation was done three times, about two months and half an hour before examintation and half an hour after examination. The result was that the migration rate of PMN 30 second (index of OMR) declines significantly just a moment before examination and recovers after examination (P<0.01). The OMR index was 0.43 well before examination, 0.23 shortly before it and 0.42 after examination. Apparently, the academic stress can temporarily inhibit some facet of the immune response showing a measurable abnormality of the index OMR. Results of this research could be useful for mental preparation of students taking examinations. Finally, this may give clue for the genesis of suggested stress related diseases which work through an immunological mechanism.