BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS

E. A. Galashina; Yu. A. Chibrikova; A. N. Ivanov; E. V. Gladkova; I. A. Norkin

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье (Nov 2020)

BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS

E. A. Galashina,
Yu. A. Chibrikova,
A. N. Ivanov,
E. V. Gladkova,
I. A. Norkin

Affiliations

E. A. Galashina: Research Institute of Traumatology, Orthopedics, and Neurosurgery, Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University,’ Ministry of Health of the Russian Federation
Yu. A. Chibrikova: Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University’, Ministry of Health of the Russian Federation
A. N. Ivanov: Research Institute of Traumatology, Orthopedics, and Neurosurgery, Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University,’ Ministry of Health of the Russian Federation
E. V. Gladkova: Research Institute of Traumatology, Orthopedics, and Neurosurgery, Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University,’ Ministry of Health of the Russian Federation
I. A. Norkin: Research Institute of Traumatology, Orthopedics, and Neurosurgery, Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University,’ Ministry of Health of the Russian Federation

Journal volume & issue: Vol. 0, no. 2
pp. 98 – 103

Abstract

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In this study, we analyzed biocompatibility of polycaprolactone/vaterite scaffolds by assessing the dynamics of systemic inflammatory response. We detected an increase in the CRP level after 7 days and no changes in the level TNF-α and IL-1β after 7 and 21 days, which indicates a weak and short-term inflammatory reaction and is a pathogenetic component of matrix biocompatibility.

Published in Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье

ISSN: 2226-762X (Print); 2782-1579 (Online)
Publisher: Private institution educational organization of higher education "Medical University "ReaViz"
Country of publisher: Russian Federation
LCC subjects: Medicine: Medicine (General)
Website: https://vestnik.reaviz.ru/

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