Exploiting the kinesin-1 molecular motor to generate a virus membrane penetration site

Madhu Sudhan Ravindran; Martin F. Engelke; Kristen J. Verhey; Billy Tsai

doi:10.1038/ncomms15496

Nature Communications (May 2017)

Exploiting the kinesin-1 molecular motor to generate a virus membrane penetration site

Madhu Sudhan Ravindran,
Martin F. Engelke,
Kristen J. Verhey,
Billy Tsai

Affiliations

Madhu Sudhan Ravindran: Department of Cell and Developmental Biology, University of Michigan Medical School
Martin F. Engelke: Department of Cell and Developmental Biology, University of Michigan Medical School
Kristen J. Verhey: Department of Cell and Developmental Biology, University of Michigan Medical School
Billy Tsai: Department of Cell and Developmental Biology, University of Michigan Medical School

DOI: https://doi.org/10.1038/ncomms15496
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 14

Abstract

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How non-enveloped viruses cross host membranes is incompletely understood. Here, Ravindranet al. show that polyomavirus SV40 recruits kinesin-1 to construct a penetration site on the ER membrane.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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