Journal of Veterinary Internal Medicine (Sep 2024)

Effects of fecal microbiota transplantation on clinical outcomes and fecal microbiota of foals with diarrhea

  • Jillian Bell,
  • Sharanne L. Raidal,
  • Rosemary S. Cuming,
  • Gareth Trope,
  • Kristopher J. Hughes

DOI
https://doi.org/10.1111/jvim.17185
Journal volume & issue
Vol. 38, no. 5
pp. 2718 – 2728

Abstract

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Abstract Background Diarrhea in foals can be associated with disruption of the intestinal microbiota (dysbiosis). Effective management of intestinal dysbiosis in foals has not been demonstrated. Hypothesis/Objectives Fecal microbiota transplantation (FMT) in foals with diarrhea influences the intestinal microbiota and improves clinical and clinicopathological outcomes. Animals Twenty‐five foals 4). Conclusions and Clinical Importance In foals with diarrhea, FMT appears safe and can be associated with some clinical and microbiota changes suggestive of beneficial effect.

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