Journal of Stress Physiology & Biochemistry (Sep 2010)
Correlation of serum IgE with stress in Indian dromedaries affected with skin wounds
Abstract
The present investigation was planned to explore stress induced changes in the levels of IgE by correlating them with the important parameters of stress like cortisol and free radical scavengers in the serum of Indian dromedaries. The mean values of serum IgE and cortisol were significantly (p ≤ 0.05) higher in wound affected dromedaries than the respective healthy values. A positive significant (p ≤ 0.05) correlation was observed between the values of serum IgE and cortisol. The mean values of serum vitamin C, vitamin E and glutathione decreased whereas of serum catalase, superoxide dismutase, monoamine oxidase, glutathione reductase, xanthine oxidase, oxidase and peroxidase increased significantly (p ≤ 0.05) from their respective healthy mean values. A negative significant (p ≤ 0.05) correlation was observed between the values of serum IgE and vitamin C; serum IgE and vitamin E and serum IgE and glutathione activities. A positive significant (p ≤ 0.05) correlation was observed between the values of serum IgE and catalase; serum IgE and superoxide dismutase; serum IgE and monoamine oxidase; serum IgE and glutathione reductase; serum IgE and xanthine oxidase; serum IgE and oxidase; and serum IgE and peroxidase activities. It was concluded that stress was able to induce marked changes in the levels of IgE in the Indian dromedaries. Wounds altered the immune status as well as levels of cortisol and free radical scavengers in the serum.
