Post-Covid disorders of nervous system: personal experience

Abstract

Introduction. In the COVID-19 pandemic, high lethality as well as long-term outcomes are getting more and more relevant. According to the accumulated study results, COVID-19 affects the nervous system both directly and indirectly. Objective: to study the variants of post-COVID syndrome based on the data from the State Novosibirsk Regional Clinical Hospital from July 2020 to February 2022. Materials and methods. We have performed post hoc analysis of the medical records of 1,500 patients with a past history of COVID-19 admitted following various neurological disorders manifested from July 2020 to February 2022. Results. While temporary and pathogenetic association with past COVID-19 was revealed in 455 patients, primary involvement of the central nervous system was reported in 91.6% of cases, primary involvement of the peripheral nervous system in 8.1% of cases, and musculoskeletal disorder (idiopathic myodystrophy) in 0.3% of cases. Conclusion. Prevalence of the neurological variants of post-COVID syndrome is still unknown. However, patients with severe COVID-19 are more susceptible to neurological complications during the following six months.

Keywords

• covid-19
• post-covid syndrome
• associated neurological variants
• guillain–barré syndrome
• autoimmune encephalomyelitis
• encephalopathy
• stroke