Emerging Infectious Diseases (Mar 2019)
Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia
Abstract
A retrospective population-based molecular epidemiologic study of multidrug-resistant Mycobacterium tuberculosis complex strains in Serbia (2008–2014) revealed an outbreak of TUR genotype strains in a psychiatric hospital starting around 1990. Drug unavailability, poor infection control, and schizophrenia likely fueled acquisition of additional resistance and bacterial fitness–related mutations over 2 decades.
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