Communications Biology (Jun 2022)

Amygdala–pons connectivity is hyperactive and associated with symptom severity in depression

  • Jing Jun Wong,
  • Nichol M. L. Wong,
  • Dorita H. F. Chang,
  • Di Qi,
  • Lin Chen,
  • Tatia M. C. Lee

DOI
https://doi.org/10.1038/s42003-022-03463-0
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 11

Abstract

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A study on patients with major depressive disorder (MDD) suggests that a specific sadness-processing connection between the amygdala and pons appears to be dysfunctional among people with MDD and associated with severity of depression.