Nature Communications (Dec 2017)
The interhemispheric CA1 circuit governs rapid generalisation but not fear memory
- Heng Zhou,
- Gui-Jing Xiong,
- Liang Jing,
- Ning-Ning Song,
- De-Lin Pu,
- Xun Tang,
- Xiao-Bing He,
- Fu-Qiang Xu,
- Jing-Fei Huang,
- Ling-Jiang Li,
- Gal Richter-Levin,
- Rong-Rong Mao,
- Qi-Xin Zhou,
- Yu-Qiang Ding,
- Lin Xu
Affiliations
- Heng Zhou
- Key Laboratory of Animal Models and Human Disease Mechanisms, and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences
- Gui-Jing Xiong
- Key Laboratory of Animal Models and Human Disease Mechanisms, and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences
- Liang Jing
- Key Laboratory of Animal Models and Human Disease Mechanisms, and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences
- Ning-Ning Song
- Key Laboratory of Arrhythmias, Ministry of Education, East Hospital, and Department of Anatomy and Neurobiology, Collaborative Innovation Center for Brain Science, Tongji University School of Medicine
- De-Lin Pu
- Key Laboratory of Animal Models and Human Disease Mechanisms, and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences
- Xun Tang
- School of Life Sciences, University of Science and Technology of China
- Xiao-Bing He
- Wuhan Institute of Physics and Mathematics, The Chinese Academy of Sciences
- Fu-Qiang Xu
- Wuhan Institute of Physics and Mathematics, The Chinese Academy of Sciences
- Jing-Fei Huang
- State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences
- Ling-Jiang Li
- Mental Health Institute, Second Xiangya Hospital of Central South University
- Gal Richter-Levin
- Department of Neurobiology and Ethology, and Department of Psychology, University of Haifa
- Rong-Rong Mao
- Key Laboratory of Animal Models and Human Disease Mechanisms, and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences
- Qi-Xin Zhou
- Key Laboratory of Animal Models and Human Disease Mechanisms, and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences
- Yu-Qiang Ding
- Key Laboratory of Arrhythmias, Ministry of Education, East Hospital, and Department of Anatomy and Neurobiology, Collaborative Innovation Center for Brain Science, Tongji University School of Medicine
- Lin Xu
- Key Laboratory of Animal Models and Human Disease Mechanisms, and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences
- DOI
- https://doi.org/10.1038/s41467-017-02315-4
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 10
Abstract
Previous work has documented a slow form of memory generalization although a rapid one is demanded. Here the authors elucidate the role of the interhemispheric CA1-CA1 projection in a form of rapid generalization of contextual fear memory via gradual potentiation of these synapses over 24 h.
