DEFINITION OF CYTOSTATIC EFFECT OF PROTARGOLUM SOLUTIONS IN DIFFERENT CONCENTRATIONS ON HUMAN DERMAL FIBROBLASTS

Abstract

This article presents the data on the effect of protargolum solutions in different concentrations on human dermal fibroblasts. For evaluation of the metabolic activity of the cells MTT-test was used. This test is based on the ability of NAD-H-adjective oxydoreductases to represent the amount of viable cells. It was determined, that the critical concentration of protargolum solution, responsible for inhibitory effect on fibroblasts proliferation is on the range 2 · 10-2 - 5 · 10-1 mg/ml.

Keywords

• nanoparticls
• colloidal silver
• cytostatic effect
• human dermal fibroblast