The Emerging Importance of Sleep Regularity on Cardiovascular Health and Cognitive Impairment in Older Adults: A Review of the Literature

Abstract

Shuo Qin, Michael WL Chee Centre for Sleep and Cognition, National University of Singapore, SingaporeCorrespondence: Michael WL Chee, Centre for Sleep and Cognition, National University of Singapore, Singapore, Email [email protected]: The regularity of sleep/wake patterns across multiple days is emerging as an important determinant of health. However, the association between sleep regularity and health outcomes in the aging population is not well understood. The current systematic review identified 22 publications that examined the relationship between sleep regularity and selected health outcomes: cardiovascular risk, cognitive impairment, and mortality. All studies were published after 2010, reflecting a growing research interest in daily sleep regularity. Low sleep regularity was consistently associated with higher cardiovascular risk and elevated risk of all-cause mortality. Results on cognitive impairment are mixed, with inconsistency likely attributed to small sample sizes and differences in sleep regularity assessment. Overall, regularity in sleep carries important information about health and should be included in future studies that collect daily sleep measures. Gaps in literature and methodological shortcomings are discussed.Keywords: sleep regularity, Aging, cardiovascular health, cognitive impairment, mortality

Keywords

• sleep regularity
• aging
• cardiovascular health
• cognitive impairment
• mortality