Frontiers in Bioinformatics (Dec 2021)

Releasing the Kraken

  • Steven L. Salzberg,
  • Steven L. Salzberg,
  • Steven L. Salzberg,
  • Steven L. Salzberg,
  • Derrick E. Wood,
  • Derrick E. Wood

DOI
https://doi.org/10.3389/fbinf.2021.808003
Journal volume & issue
Vol. 1

Abstract

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Ten years ago, the dramatic rise in the number of microbial genomes led to an inflection point, when the approach of finding short, exact matches in a comprehensive database became just as accurate as older, slower approaches. The new idea led to a method that was hundreds of times times faster than those that came before. Today, exact k-mer matching is a standard technique at the heart of many microbiome analysis tools.

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