Nature Communications (May 2021)

Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice

  • Can Liu,
  • Chia-Ying Lee,
  • Greg Asher,
  • Liqin Cao,
  • Yuka Terakoshi,
  • Peng Cao,
  • Reiko Kobayakawa,
  • Ko Kobayakawa,
  • Katsuyasu Sakurai,
  • Qinghua Liu

DOI
https://doi.org/10.1038/s41467-021-22914-6
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

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Innate and learned fear can induce rapid changes in body temperature of mammals. The authors identify the posterior subthalamic nucleus as a major thermoregulatory hub that connects the external lateral parabrachial subnucleus to the nucleus of the solitary tract to mediate fear-evoked hypothermia.