Nature Communications (Aug 2019)

Camouflaging bacteria by wrapping with cell membranes

  • Zhenping Cao,
  • Shanshan Cheng,
  • Xinyue Wang,
  • Yan Pang,
  • Jinyao Liu

DOI
https://doi.org/10.1038/s41467-019-11390-8
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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The use of engineered bacteria for biomedical applications is limited by side effects such as inflammatory response. Here the authors engineer cell membrane coated bacteria as in vivo tumor imaging agents, and show that these generate a lower inflammatory response and reduced macrophage clearance.