Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applications

Abstract

Metabolomics is a rapidly growing field that aims to understand the complex metabolic pathways involved in health and disease. Liquid chromatography mass spectrometry (LC-MS) based untargeted metabolomics has emerged as a powerful tool for investigating the metabolic changes associated with various diseases, and for identifying potential biomarkers for early disease detection and treatment monitoring. This review provides a comprehensive overview of LC-MS based untargeted metabolomics and its clinical applications.

Keywords

• untargeted metabolomics
• lc-ms
• clinical applications
• biomarker
• personalized medicine