Advances in the Use of Regional Homogeneity from Resting-state Functional MRI for the Diagnosis of Insomnia in Depressive Disorder

Abstract

Insomnia is a common concomitant symptom in patients with depressive disorder. Early and effective assessment of insomnia symptoms in these patients is the key to preventing sleep problems and delaying the deterioration of depression disorder. Currently, the effectiveness of subjective and objective sleep assessment tools has often been expounded in relevant reviews, but the assessment indicators related to insomnia in depressive disorder, and rs-fMRI technique, an objective sleep assessment tool, have been rarely reviewed. We reviewed the latest advances in the use of regional homogeneity from resting-state functional MRI for the diagnosis of insomnia in major depressive disorder, and described its use in the differentiation between unipolar and bipolar disorders, with a view to providing theoretical and practical evidence for clinical diagnosis, differentiation, and treatment of unipolar and bipolar disorders, and for relevant studies.

Keywords

• sleep initiation and maintenance disorders|insomnia|depression|fmri|reho|review