Analysis of ARMD related risk factors and establishment of Nomoto prediction model in high altitude area

Abstract

AIM: To determine the risk factors of age-related macular degeneration(ARMD)in high altitude areas and establish Nomoto prediction model.METHODS:Using the method of cluster random sampling, the subjects were selected from some communities in Xining City, with an average altitude of 2 100m. The subjects were ≥40 years old, and the investigation method was field investigation. Single factor and multi factor analysis were used to determine the risk factors of ARMD, and R software was used to draw Nomoto.RESULTS: The actual number of subjects in this survey is 2 595. Age, cataract, living time at high altitude, smoking, drinking, high blood pressure and mobile phone use are risk factors of ARMD. Old age was the most risk factor for ARMD(OR: 53.078, 95% CI: 28.405-77.183, POR: 9.142, 95% CI: 1.906-43.846, PCONCLUSION: The risk factors of ARMD are old age, high altitude living time, cataract, smoking, drinking, high blood pressure and mobile phone using time, especially the old people who live in high altitude for a long time. Nomo scoring system can accurately predict ARMD and provide theoretical basis for clinicians to intervene ARMD in high altitude areas.

Keywords

• high altitude area
• age-related macular degeneration
• prevalence
• risk factor
• nomo score