Immunogenic Properties of Cell Wall Preparations of Francisella tularensis Different Subspecies in Experimental Tularemia

A. V. Korneva; V. B. Nikolaev; T. A. Ivanova; V. I. Dubrovina; G. B. Mukhturgin; E. Yu. Markov; T. P. Starovoitova; A. V. Mazepa; T. T. Shkaruba; S. V. Balakhonov

doi:10.31631/2073-3046-2018-17-2-46-49

Эпидемиология и вакцинопрофилактика (Apr 2018)

Immunogenic Properties of Cell Wall Preparations of Francisella tularensis Different Subspecies in Experimental Tularemia

A. V. Korneva,
V. B. Nikolaev,
T. A. Ivanova,
V. I. Dubrovina,
G. B. Mukhturgin,
E. Yu. Markov,
T. P. Starovoitova,
A. V. Mazepa,
T. T. Shkaruba,
S. V. Balakhonov

Affiliations

A. V. Korneva: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
V. B. Nikolaev: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
T. A. Ivanova: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
V. I. Dubrovina: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
G. B. Mukhturgin: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
E. Yu. Markov: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
T. P. Starovoitova: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
A. V. Mazepa: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
T. T. Shkaruba: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing
S. V. Balakhonov: Irkutsk Antiplague Research Institute of of Federal Service of Surveillance on Consumer' Rights Protection and Human Wellbeing

DOI: https://doi.org/10.31631/2073-3046-2018-17-2-46-49
Journal volume & issue: Vol. 17, no. 2
pp. 46 – 49

Abstract

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Immunogenic properties of cell wall (CW) preparations of Francisella tularensis four subspecies are investigated. It is shown that the preparations from F. tularensis urea lysates are not toxic for experimental animals. Besides, CW of F. tularensis А-61 subsp. mediasiatica and F. tularensis B-399 A-Cole subsp. tularensis possess immunogenic activity in experimental tularemia caused by F. tularensis 306 subsp. holarctica.

Published in Эпидемиология и вакцинопрофилактика

ISSN: 2073-3046 (Print); 2619-0494 (Online)
Publisher: Numikom LLC
Country of publisher: Russian Federation
LCC subjects: Philosophy. Psychology. Religion: Speculative philosophy: Epistemology. Theory of knowledge
Website: https://www.epidemvac.ru

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