Journal of Cardiovascular Development and Disease (Sep 2022)

Life-Space Activities Are Associated with the Prognosis of Older Adults with Cardiovascular Disease

  • Kakeru Hashimoto,
  • Akihiro Hirashiki,
  • Koharu Oya,
  • Junpei Sugioka,
  • Shunya Tanioku,
  • Kenji Sato,
  • Ikue Ueda,
  • Naoki Itoh,
  • Manabu Kokubo,
  • Atsuya Shimizu,
  • Hitoshi Kagaya,
  • Izumi Kondo

DOI
https://doi.org/10.3390/jcdd9100323
Journal volume & issue
Vol. 9, no. 10
p. 323

Abstract

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Life-space activities are a measure of daily activity level. Here, we examined the association between life-space activities and prognosis in 129 cardiovascular diseases (CVD) patients 65 years of age or older (average age, 79.2 ± 7.6 years; mean left ventricular ejection fraction, 56.7 ± 13.2%) who had been admitted to our hospital for worsening CVD. Subjects were followed, and the primary endpoints were cardiovascular hospitalization and cardiovascular death. Receiver operating characteristic analysis produced a cutoff value for life-space assessment (LSA) score for increased risk of cardiovascular hospitalization for two years of 53.0 points (sensitivity, 55.9%; specificity, 82.1%). Kaplan–Meier analysis using this cutoff value revealed that the rates of cardiovascular hospitalization and cardiovascular death were significantly higher in subjects with an LSA score below the cutoff than in those with a score above the cutoff (both p p = 0.023) and cardiovascular death (HR, 15.223; 95% CI, 1.689–137.180; p = 0.015), even after adjusting for age, sex, left ventricular ejection fraction, and log-transformed brain natriuretic peptide level. Thus, life-space activities are associated with prognosis in older adults with CVD.

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