Mathematical Biosciences and Engineering (Aug 2024)

Understanding the oscillations of an epidemic due to vaccine hesitancy

  • Anthony Morciglio,
  • R. K. P. Zia,
  • James M. Hyman,
  • Yi Jiang

DOI
https://doi.org/10.3934/mbe.2024299
Journal volume & issue
Vol. 21, no. 8
pp. 6829 – 6846

Abstract

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Vaccine hesitancy threatens to reverse the progress in tackling vaccine-preventable diseases. We used an $ SIS $ model with a game theory model for vaccination and parameters from the COVID-19 pandemic to study how vaccine hesitancy impacts epidemic dynamics. The system showed three asymptotic behaviors: total rejection of vaccinations, complete acceptance, and oscillations. With increasing fear of infection, stable endemic states become periodic oscillations. Our results suggest that managing fear of infection relative to vaccination is vital to successful mass vaccinations.

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