Frontiers in Surgery (Aug 2022)

Aggressive angiomyxoma: The first case report in skull

  • Zexin Cao,
  • Zexin Cao,
  • Lifeng Miao,
  • Min Liu,
  • Wenyu Liu,
  • Wenyu Liu,
  • Hengrui Zhang,
  • Hengrui Zhang,
  • Xuchen Liu,
  • Xuchen Liu,
  • Jiwei Wang,
  • Jiwei Wang,
  • Xinyu Wang,
  • Xinyu Wang

DOI
https://doi.org/10.3389/fsurg.2022.985739
Journal volume & issue
Vol. 9

Abstract

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Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor primarily growing in the soft tissue of the pelvis and perineum in women of reproductive age. It is a benign tumor that still has a probability of being accompanied by localized invasion. Although negative margins of resection are difficult to achieve due to the invasive nature of the tumor and the lack of a well-defined capsule, the first line of treatment for AAM is surgery. The diagnosis of AAM is difficult to make due to a lack of specific manifestations and specific tumor markers. In this study, we reported a case of aggressive angiomyxoma in a 2-year-old girl that rarely develops in the skull with craniocerebral compression. The patient initially had a mass on her head that attracted the attention of her family, and then she began to have episodic headaches. Surgery was performed after hospitalization, and the tumor recurred 1 year after the operation, around the originally affected skull.

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