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CHIMIA
(May 2023)
Understanding Intrinsic Warhead Reactivity and Cysteine Druggability in Covalent Drug Discovery
Chiara Borsari,
Alexandra Ioana Corfu,
Paola Conti
Affiliations
Chiara Borsari
Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milano, Italy
Alexandra Ioana Corfu
Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milano, Italy
Paola Conti
Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milano, Italy
DOI
https://doi.org/10.2533/chimia.2023.349
Journal volume & issue
Vol. 77, no. 5
Abstract
Read online
No abstracts available.
Keywords
Covalent inhibitors
Druggable cysteines
Intrinsic reactivity
Rational Design
Warhead
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