Enhancing Quality in Hematology Laboratory Testing: A Comprehensive Review of Preanalytical Phase Errors and Prevention Strategies

Abstract

This comprehensive review explores the critical importance of the preanalytical phase in hematology laboratory testing and its significant impact on the overall quality of results. The preanalytical phase encompasses all the processes from sample collection to sample preparation, and any errors during this stage can lead to inaccurate and unreliable hematological data. By systematically examining the various sources of preanalytical errors, including specimen collection, transportation, and handling, this review provides insights into the potential challenges faced in the hematology laboratory. Furthermore, the article discusses a range of effective prevention strategies to mitigate preanalytical phase errors and enhance the reliability of hematological test results. These strategies encompass improvements in staff training, standardization of collection procedures, implementation of quality control measures, and advancements in technology and automation. The review emphasizes the importance of fostering a culture of awareness and adherence to best practices in the laboratory setting. Preanalytical errors remain a major concern in every laboratory because the majority of the stages leading up to these errors are not within the direct control of the laboratory. Even though they cannot be eliminated, they can definitely be minimized. The preanalytical errors of a hematology laboratory can be reduced with the help of quality management systems, personnel training, regular audits, and automation in the preanalytical stage, thus increasing the accuracy of the results and providing better patient care.

Keywords

• hematology laboratory
• preanalytical errors
• sample collection
• sample handling
• specimen contamination