Di-san junyi daxue xuebao (Mar 2021)

Prevalence and risk factors of diabetic kidney disease in patients with diabetes in urban and rural communities in Chongqing, China

  • DENG Xiuyuan,
  • JIANG Youzhao,
  • DENG Wuquan,
  • CHEN Bing

DOI
https://doi.org/10.16016/j.1000-5404.202010013
Journal volume & issue
Vol. 43, no. 5
pp. 452 – 457

Abstract

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ObjectiveTo investigate the prevalence and risk factors of diabetic kidney disease (DKD) among the patients with type 2 diabetes mellitus (T2DM) in rural and urban communities in the Chongqing Main City. MethodsA total of 735 T2DM patients from rural and urban communities in the Chongqing Main City were selected by stratified cluster random sampling. They were compared in terms of demographic characteristics, physical test results, metabolic indicators, compliance rate of diabetes comprehensive control and DKD prevalence. Multivariate logistic regression model was used to analyze the risk factors of DKD. Results①The prevalence of DKD was 31.3% in the T2DM patients, and was higher in the rural communities than that in the urban communities (35.9% vs 28.1%, P<0.01). ② There were statistical differences in the demographic characteristics, physical test results, metabolic indicators, and compliance rates between the patients from the urban and rural communities (P<0.05). ③ Systolic blood pressure (SBP, OR=2.393), course of diabetes (OR=2.471) and level of triglyceride (TG, OR=1.988) were independent risk factors, while taking ACEI (angiotensin converting enzyme inhibitors) or ARBs (angiotensin-receptor blockers, OR=0.163) were protective factors for DKD in the patients of rural communities. And, age (OR=1.682), SBP (OR=2.201), course of diabetes (OR=1.644), HbA1c (OR=2.844), uric acid (OR=2.182) were independent risk factors for those in the urban communities. ConclusionThe prevalence of DKD is higher in the rural communities than that in the urban communities. Attention should be paid to hyperlipidemia in rural communities. Blood glucose control should be strengthened in urban communities, and physicians should correct hyperuricemia and pay attention to the DKD screening in elderly population.

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