Label-Free DNA Detection with Capacitive Field-Effect Devices—Challenges and Opportunities

Michael J. Schöning; Thomas S. Bronder; Chunsheng Wu; Sabrina Scheja; Max Jessing; Christoph Metzger-Boddien; Michael Keusgen; Arshak Poghossian

doi:10.3390/proceedings1080719

Proceedings (Nov 2017)

Label-Free DNA Detection with Capacitive Field-Effect Devices—Challenges and Opportunities

Michael J. Schöning,
Thomas S. Bronder,
Chunsheng Wu,
Sabrina Scheja,
Max Jessing,
Christoph Metzger-Boddien,
Michael Keusgen,
Arshak Poghossian

Affiliations

Michael J. Schöning: Institute of Nano- and Biotechnologies (INB), FH Aachen University of Applied Sciences, 52428 Jülich,Heinrich-Mußmann-Str. 1, Germany
Thomas S. Bronder: Institute of Nano- and Biotechnologies (INB), FH Aachen University of Applied Sciences, 52428 Jülich,Heinrich-Mußmann-Str. 1, Germany
Chunsheng Wu: Institute of Nano- and Biotechnologies (INB), FH Aachen University of Applied Sciences, 52428 Jülich,Heinrich-Mußmann-Str. 1, Germany
Sabrina Scheja: Institute of Nano- and Biotechnologies (INB), FH Aachen University of Applied Sciences, 52428 Jülich,Heinrich-Mußmann-Str. 1, Germany
Max Jessing: Institute of Nano- and Biotechnologies (INB), FH Aachen University of Applied Sciences, 52428 Jülich,Heinrich-Mußmann-Str. 1, Germany
Christoph Metzger-Boddien: gerbion GmbH & Co KG, 70806 Kornwestheim, Remsstr. 1, Germany
Michael Keusgen: Institute of Pharmaceutical Chemistry, Philipps University Marburg, 35032 Marburg,Marbacher Weg 6-10, Germany
Arshak Poghossian: Institute of Nano- and Biotechnologies (INB), FH Aachen University of Applied Sciences, 52428 Jülich,Heinrich-Mußmann-Str. 1, Germany

DOI: https://doi.org/10.3390/proceedings1080719
Journal volume & issue: Vol. 1, no. 8
p. 719

Abstract

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Field-effect EIS (electrolyte-insulator-semiconductor) sensors modified with a positively charged weak polyelectrolyte layer have been applied for the electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge. [...]

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Published in Proceedings

ISSN: 2504-3900 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: General Works
Website: http://www.mdpi.com/journal/proceedings

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