Nutrients (Jan 2023)

Association between the Triglyceride-Glucose Index and Vitamin D Status in Type 2 Diabetes Mellitus

  • Qunyan Xiang,
  • Hui Xu,
  • Junkun Zhan,
  • Shuzhen Lu,
  • Shuang Li,
  • Yanjiao Wang,
  • Yi Wang,
  • Jieyu He,
  • Yuqing Ni,
  • Linsen Li,
  • Yiyang Liu,
  • Youshuo Liu

DOI
https://doi.org/10.3390/nu15030639
Journal volume & issue
Vol. 15, no. 3
p. 639

Abstract

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Background: Vitamin D deficiency (VDD) increases the risk for type 2 diabetes mellitus (T2DM), which might be related to insulin resistance (IR). We aimed to explore the association between the triglyceride-glucose (TyG) index, a reliable indicator of IR, and VDD in patients with T2DM. Methods: There were 1034 participants with T2DM enrolled in the Second Xiangya Hospital of Central South University. The TyG index was calculated as ln (fasting triglyceride (TG, mg/dL) × fasting blood glucose (mg/dL)/2). VDD was defined as 25-hydroxyvitamin D [25(OH)D] level p < 0.05). Conclusions: Patients with higher TyG index were more likely to have an increased risk of VDD in T2DM population, which may be related to IR.

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